Comparative transcriptomics of nematodes C. elegans and Brugia malayi supports Ohno’s hypothesis of X-linked genes showing upregulation following Y degeneration, which depends on the dosage-sensitive gene content of proto-X.
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New chromosome-level genome assemblies for hexaploid weeds Conyza sumatrensis and C. bonariensis. These resources will serve to inform research into evolution and management of these species.
Armstrong et al. estimate de novo germline mutation rates across all extant Panthera species and the Clouded leopard using pedigrees. Reported rates align with other mammals, and can help refine models for phylogenetic and demographic analyses.
https://www.europesays.com/uk/6742/ Genetic breakthrough in psychiatry using long-read genomic sequencing #Autism #Children #Disability #DNA #Gene #Genetic #Genetics #Genome #Genomic #GenomicSequencing #Medicine #MentalHealth #Psychiatry #Research #Science #Syndrome #Technology #UK #UnitedKingdom
How #genome-wide sequence divergence maps to species status https://www.pnas.org/doi/10.1073/pnas.2319389122 #biodiversity #genomics
Finally, I can make sure I'm a human, not a rat!
**tgv**: Terminal Genome Viewer
Explore human genomes in the terminal.
Supports multiple formats, Vim motions & more!
Written in Rust & built with @ratatui_rs
GitHub: https://github.com/zeqianli/tgv
GIF
The European Reference Genome Atlas (ERGA) is a community initiative coordinating the production of a reference #genome for all eukaryotic species in Europe. https://en.wikipedia.org/wiki/European_Reference_Genome_Atlas #Biodiversity #Genomics
en.wikipedia.orgEuropean Reference Genome Atlas - Wikipedia
We are happy to invite interested parties to the second talk in our new cycle of hybrid #Bioinformatics Seminar hosted jointly by #CEITEC and Faculty of Informatics at the Masaryk University Brno, Czech Republic.
Our online guest today will be Andrea Guarracino from University of Tennessee to talk about his work on #pangenomes
The webinar starts today (Mar 19) at 4PM via an MS Teams link (click the title) available at:
Bioinformatics Group at FI MU · IV106 Bionformatics seminarWe will host guests, mostly online, in the seminar in Spring 2025. Between the public seminars, students will prepare their own presentations for class only. The themes for student presentations this semester will be i) bioinformatics approaches to non-B DNA, and ii) bioinformatics for long-read sequencing and structural variant detection. Public seminar guests will be shared with a “sister seminar” at CEITEC, described here:
The Bioinformatics Seminar is a seminar series organized together with the Faculty of Informatics in the interdisciplinary fields of Bioinformatics, Biostatistics, and Computational Biology.
Allez j'ai fait 2 #dayofpractice (#100daysofpractice) d'affilés ! Basta -> gros weekend boulot en perspective. #bass #basse #sadowsky #reaper #genome #metallica #cliffburton #noremorse Alors un grand souvenir d'adolescence.
J'espère que vous appréciez la mise en scène ^^ :)
ERGA BioGenome Analysis & Applications Seminar
Monday, February 24th 2025 - 11:00 AM CET
https://www.erga-biodiversity.eu/post/structural-variation-in-the-barley-pangenome-and-the-tritex-pipeline-for-plant-genome-assembly
#biodiversity #genomics #genome #evolution
ERGA · Structural Variation in the Barley Pangenome and the TRITEX Pipeline for Plant Genome AssemblyJoin the first ERGA BioGenome Analysis & Applications Seminar of 2025! This month featuring talks by Martin Mascher and Marina Pupke Marone from the Leibniz Institute of Plant Genetics and Crop Plant Research (IPK). More details below.🕚 Monday, February 24th 2025 - 11:00 AM CET📅 Add the seminar to your calendarJoin us live on YouTube:Structural Variation in the Barley Pangenome and the TRITEX Pipeline for Plant Genome AssemblyStructural variation in the pangenome of wild and domesticated barl
Asian honeybee 
Apis cerana #pangenome - mapping & exploring genetic feature variations across populations, examining their roles #evolution & environmental adaptation https://onlinelibrary.wiley.com/doi/abs/10.1111/1755-0998.13905 #gene #genome #biodiversity
A complex #molecular machine, the #spliceosome, ensures that the #genetic information from the #genome, after being transcribed into ##mRNA precursors, is correctly assembled into mature mRNA.
#Biomolecular #Biochemistry #Genetics #sflorg
https://www.sflorg.com/2025/02/bmod02072501.html
www.sflorg.comSpliceosome: How Cells Avoid Errors When Manufacturing MrnaStructural biologists provide a first-time look at the atomic level into the quality control mechanism of this complex molecular machine
The European Reference #Genome Atlas ( @erga_biodiv ) Community Genomes https://www.youtube.com/watch?v=R1mnSTrNJ6s&list=PL4qmCfIUT9K_UuDbkZH5gDYkjeZwDDqT1&index=6 Supporting individual research groups to participate in global coordination efforts for European #biodiversity
#Mosquito #genome chromatin architecture #evolution - extremely long-ranged looping interactions, conserved for ~100 million years https://www.nature.com/articles/s41467-022-29599-5
NatureAnopheles mosquitoes reveal new principles of 3D genome organization in insects - Nature CommunicationsAnopheles mosquitoes are vectors of human malaria, and better understanding of them has implications for public health. Here, the authors apply Hi-C, FISH, RNA-seq, and ChIP-seq techniques to comprehensively characterize chromatin architecture and its evolutionary dynamics in five Anopheles species.
#A3Cat also summarises ongoing #genome sequencing efforts for #arthropods with information collated from the Genomes on a Tree resource https://a3cat.unil.ch/upcoming_assemblies.html
Our last #commonancestor lived 4.2 billion years ago—perhaps hundreds of millions of years earlier than thought
#Genomes of diverse #microbes point to early #evolution of a rudimentary #immunesystem
The last ancestor shared by all living organisms was a microbe that lived 4.2 billion years ago, had a fairly large #genome encoding some 2600 proteins, enjoyed a diet of hydrogen gas and carbon dioxide, and harbored a rudimentary immune system for fighting off viral invaders.
https://www.science.org/content/article/our-last-common-ancestor-lived-4-2-billion-years-ago-perhaps-hundreds-millions-years
UPDATE: #Arthropod #Genome Assembly Assessment Catalogue: #A3Cat v.2025-01-01 
Well interesting, #matrilocality of the Durotriges people:
'In southern Britain, the Late Iron Age Durotriges tribe often buried women with substantial grave goods. Here we analyse 57 ancient genomes from Durotrigian burial sites and find an extended kin group centred around a single maternal lineage, with unrelated (presumably inward migrating) burials being predominantly male. Such a matrilocal pattern is undescribed in European prehistory, but when we compare mitochondrial haplotype variation among European archaeological sites spanning six millennia, British Iron Age cemeteries stand out as having marked reductions in diversity'
NatureContinental influx and pervasive matrilocality in Iron Age Britain - NatureAn analysis of ancient mitochondrial and nuclear DNA shows evidence of matrilocal communities in Iron Age Britain.
Join us at #PAG for our workshop "Galaxy for NGS Data Analysis: A Hands-on
Workshop." gxy.io/pag25-webpage We will be talking about #workflows, particularly related to #genome #assembly and #annotation. 4:00PM (ie, in less than an hour!) in Town and Country D. #UseGalaxy #Galaxy